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Consideration by an advisory committee is not the same as approval or a finding that these substances are safe and effective

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Sperm DNA fragmentation is a clinically validated predictor of pregnancy loss 51 , and its reduction from 8.3% (control) to 5.0% at 100 g/mL, approaching the 5% AI semen quality threshold, likely contributed to improved embryo survival following cervical insemination

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The second therapy, MK-1167, is an investigational oral treatment that is taken along with donepezil, an approved acetylcholineraste inhibitor, to improve symptoms of Alzheimers