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The primary role of Phentermine is to bridge the gap between willpower and biology

However, GI side effects including GI bleeding may occur, particularly at high doses or with long-term use

The prescriber should still evaluate the diagnosis, available approved alternatives, evidence quality, contraindications, potential interactions, monitoring plan, and whether the proposed benefit justifies uncertainty

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The combination of training-induced mTOR activation plus IGF-1 LR3 may produce synergistic effects