Semaglutide and tirzepatide are FDA-approved prescription drugs, manufactured and distributed under controlled supply chains for clinical use
Notably, GLP-1-producing neurons within the nucleus tractus solitarius (NTS) project axons to the VTA and other limbic structures, further embedding GLP-1 signaling within neural networks that regulate reward and motivation (Llewellyn-Smith et al., 2011
8% with placebo, Table 3)
The primary goal of this article is to emphasize the extensive benefits of using GLP-1RAs in treating a broad spectrum of diseases, such as obesity, cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD), neurodegenerative diseases, musculoskeletal inflammation, and various forms of cancer
Those numbers may be an underestimation, as state-licensed pharmacies that dont outsource facilities arent required to report such incidents
J Atheroscler Thromb 2023;30:74-86.PubMed 76