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Using scientifically substantiated ingredients and appropriate documentation can help support structure-function claims, but brands should separately substantiate any claim that an ingredient addresses an effect associated with GLP-1 medication use or rapid or significant weight loss

They come with nasty side effects like nausea, vomiting, diarrhea, and constipation

Still, significant hurdles remain

Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycemic control in subjects with type 2 diabetes