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For Wegovy, there is also TGA approval for: Adolescents aged 12+ with obesity (BMI 95th percentile on age and sexspecific charts, and weight over 60 kg), as an adjunct to lifestyle measures

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These findings suggest that MOTS-c may play a role in bone health and integrity, making it a potential subject of research in the context of osteoporosis

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specific MASH Phase 3 program with histological endpoints Cardiovascular risk reduction in obesity Semaglutide SELECT trial demonstrated 20% MACE reduction