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Food supplements should not be used as a substitute for a varied diet

Results of the AIM-HIGH ( Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes ) [203] and HPS2-THRIVE ( The Heart Protection Study 2Treatment of HDL to Reduce the Incidence of Vascular Events ) [204] studies contributed to a virtual lack of use of niacin in lipid-lowering therapy

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Some studies found minimal impact on hormone levels, while others documented delayed absorption peaks

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