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Some outcomes are already supported by large trials
Heartburn on tirzepatide follows similar patterns
Weeks 14: 0.25 mg once a week Weeks 58: 0.5 mg Weeks 912: 1 mg Weeks 1316: 1.7 mg (if needed) Week 17 and beyond: 2.4 mg (maintenance) Weeks 14: 2.5 mg weekly (starting dose) Week 5+: 5 mg weekly Increase by 2.5 mg every 4 weeks if needed Maximum: 15 mg weekly Your provider will help you determine the right pace based on how youre responding
But the nature of side effects differs significantly, with tirzepatide causing primarily transient gastrointestinal symptoms versus Qsymia's potential for sustained cardiovascular and neurological effects requiring ongoing monitoring
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