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and 0.33g of compound 1 was dissolved in 100mL of acetonitrile, and then added dropwise to the above mixture to react at 0 to 5 for 3 hours, the resulting reaction solution was adjusted to pH 6.0 with phosphoric acid, and then 2 times of purified water was added, and centrifugation was carried out to obtain solid compound 2, the liquid chromatogram of FIG

CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache

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Because Crohns causes inflammation of the intestinal tract, it not only interferes with B12 absorption but can cause more severe symptoms like arthritis, skin problems, fevers, rectal bleeding, and abdominal pain

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Kenji Hara received Grant-in-Aid for Scientific Research (KAKENHI), Grant Number 23K10720 from Japan Society for the Promotion of Science (JSPS)