For most folks its a cosmetic issue and nothing more
Low dose (0.1 mg/kg/d) can promote fat breakdown, reduce serum triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C)
David Sinclair Anti-aging scientists discovered that when NAD+ levels decrease, it accelerates the aging process by turning off the Sirtuins gene, causing inflammation in cells, and vice versa, if the body receives a high NAD+ dose, it opens up the function of this gene
Maldonado EN, Lemasters JJ
The use of Fer-1 and iron chelators also has a good protective effect on neurons 9,66
Probiotics (live beneficial microorganisms), prebiotics (selectively fermentable substrates), and postbiotics (microbial-derived metabolites or functional components) represent complementary approaches aimed at improving gut microbial composition and function, thereby potentially reinforcing incretin signaling and metabolic outcomes (108)