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The inward eutrophic remodelling involves reduction in the size of the lumen, media thickening, improved media to lumen ratio, and little alteration in the cross-sectional area of the media [76], while the hypertrophic remodelling involves an enhancement in the cross-sectional area of the vascular wall, size of the cell and accumulation of ECM proteins like collagen and fibronectin [77]

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