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*Correspondence: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

Furthermore, translocated bacterial lipopolysaccharides activate Toll-like receptors and the NLRP3 inflammasome, exacerbating kidney damage and fibrosis

Both peptides have become widely recognised within scientific literature due to their defined molecular structures, analytical stability and extensive use in peptide-focused research programmes

Selenium Supplementation (Critical for Glutathione Recycling) Why it works: Selenium is a cofactor for glutathione peroxidase (GPx) , the enzyme that uses glutathione to neutralize hydrogen peroxide and recycles oxidized GSSG back to reduced GSH

Antioxidants fight off oxidative stress by quenching free radicalsreactive compounds that can impact cells and tissues in the body

The Be(2)-C cell line showed greater resistance with IC50s higher than other tested cell lines