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Vitamin B12 deficiency can result in extreme fatigue, breathlessness, headaches, palpitations, and loss of appetite

Out of 167 still bottled waters which the Fine Water Society has data on, none have a pH below 5, and amongst sparkling waters only Voss sparkling water is below the level at 4.8

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Importantly, food intake remained unchanged in treated animals, suggesting the compound's effects relate to energy expenditure pathways rather than appetite