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Importantly, these phenotypes contrast with the non-inducible liver-specific Gclc KO mouse strain ( Gclc f/f Albumin-Cre), which develops liver failure and dies shortly after birth 30

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Souza SJ, Petrilli AA, Teixeira AM, Pontilho PM, Carioca AA, Luzia LA, et al

Strategies targeting metabolic vulnerabilities will not only eliminate backup systems to prevent ferroptosis [49] , but also receive considerable attention in cancer therapeutics [54]