PMCID: PMC9168854
Genetic polymorphisms in NMDAR subunits, such as NR1 and NR2B, influence individual sensitivity to the therapeutic and toxic effects of ketamine ( Comorbid conditions, such as diabetes and chronic kidney disease, amplify ketamines neurotoxicity by increasing oxidative stress and impairing drug metabolism
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Koppula et al., 2018
Siegel, 1961): Absorption tests with food, using a flushing vitamin B12 injection to estimate absorption, indicate a reduction of the passive absorption by about 40% when supplements are taken with food rather than when fasting
The Neurocognition Index (NCI) is calculated based on five tasks: memory, psychomotor speed, reaction time, complex attention, and cognitive flexibility
