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27 Inflammation Obesity associated with overnutrition induces macrophage infiltration and chronic hypoxia, causing low-grade inflammation in the adipose tissue 28 and the release of proinflammatory factors such as interleukin (IL)-1 and tumor necrosis factor (TNF-), 29,30 thus impairing insulin signaling pathway in a number of ways

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Bioinformatics 26 , 139140 (2010)

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Immunolabeling assay for Cntfr and lumenal domain of Syt1 To label Cntfr, 15 DIV primary hippocampal neurons were incubated with rabbit anti-CNTFR (extracellular) antibodies (1:50 dilution, Alomone ACR-051, RRID: AB-2340925) in conditioned media at 37 C for 40 min

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