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A gradient of exactly the same density profile can be generated by diluting OptiPrep with buffered saline, balanced salt solution or culture medium to give the same % (w/v) iodixanol solutions

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doi: 10.1002/cpt.2430 [DOI] [PubMed] [Google Scholar] 7.Parks M, Rosebraugh C

This flavanol is partially soluble in hot water, but practically insoluble in cold water and dissolvable in alcohol