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SURPASS-1 demonstrated HbA1c reductions of up to 2.07% as monotherapy

If its use is required, a reduced continuous infusion rate should be advised for infants with GA under 32 weeks, as their immature metabolic pathways slow drug clearance and place them at higher risk of accumulating excessive plasma concentrations during prolonged sedation or analgesic therapy (272)

Mechanism of multi-organ injury in experimental COVID-19 and its inhibition by a small molecule peptide

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