Clinical Nutrition
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Samples were lyophilized at 80 C and 50 mTorr for 48 h using a Telstar LYOQuest-85 freeze dryer (Telstar, Madrid, Spain) and stored at 80 C until analysis by UPLC-HRMS
The major component in the SP was n-hexadecanoic acid (palmitic acid, 28.89%), so the docking was performed by using n-hexadecanoic acid
Murata et al., 2019)
However, discontinuation of therapy resulted in worsening glycemic control, reflected by HbA1c, fasting and 2-hour post prandial glucose, as well as a decline in -cell function after a 9-month washout period (112)