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Luca Bernardi Institution: Karolinska Institutet, Sweden Result: Hypothalamic organoids engineered from stem cells were transplanted into models with disrupted circadian genes

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The protective association was also not observed in participants who used tobacco or those with atherosclerotic disease

This suggests that decreased caloric intake can drive the initial periods of weight loss, but when weight reduction reaches 10%, decreases in energy expenditure begin with increasing strong driving forces of hunger to try to slow the weight loss process

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8.6 Scientific integrity and responsible framing From a scientific-integrity standpoint, the renewed interest in underexplored peptide systems carries an obligation to avoid overstated claims and selective citation