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We obtained the entries for the responsible metabolic enzymes from the BRaunschweig ENzyme DAtabase (BRENDA) database 81 and extracted their allosteric effector (activator and inhibitor) information and inhibitory half-saturation constants (K i ) values, as reported for Homo sapiens , Mus musculus , and Rattus norvegicus

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The NADPH takes part in the biosynthesis that reduces cholesterol and oil acids and also in the synthesis of the nitric oxide (NO)

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