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Efficacy and safety of cAMP-biased GLP-1 receptor agonist ecnoglutide versus dulaglutide in patients with type 2 diabetes and elevated glucose concentrations on metformin monotherapy (EECOH-2): a 52-week, multicentre, open-label, non-inferiority, randomised, phase 3 trial

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Although the methodological quality of the included studies was variable (scores ranging from 22 to 82), the overall findings support the clinical efficacy of extracorporeal SWT in aesthetic indications.52 While the data pertain specifically to cellulite, the underlying mechanisms improved lymphatic flow, microvascular function, and connective tissue remodeling are also pathophysiologically relevant to lipedema

Its involvement in lipid metabolism and the management of obesity extends to controlling energy expenditure [31]

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