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Cholinergic anti-inflammatory pathways Neurotransmitters, specifically adenosine triphosphate (ATP) and acetylcholine (ACh), are responsible for mediating the activation or initiation of contractions in the urinary bladders smooth muscle through the engagement of purinergic and/or muscarinic receptors (Tsai et al., 2012)

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a , Individual sgRNA scores of SLC25A40 and TXNRD2 from the CRISPR screens in indicated cell lines from Fig