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Binding occupancy climbs about six-fold (roughly 7% to 42%) across the ladder and tracks the weight effect

102 RossnerP.CervenaT.Vojtisek-LomM.VrbovaK.AmbrozA.NovakovaZ.et al (2019)

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J.MussaS.KhooJ.CaiS.GuzikT.JeffersonA.et al (2003)

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Given that FoxO factors are known to govern the cell cycle and apoptosis, control over this pathway by melatonin enhances the anti-cancer properties of melatonin due to apoptosis induction and the inhibition of tumor proliferation [113]