High-fat and fried foods often trigger nausea because semaglutide slows stomach emptying and heightens digestive sensitivity
This is typically the dose tier where researchers begin to notice significant appetite suppression and where tirzepatide appetite effects become most pronounced
Cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation) have also been reported
* Wegovy 7.2mg dose is taken slightly differently
In these five phase-3 trials, the efficacy of various tirzepatide doses were compared to a placebo, a GLP-1 receptor agonist (1mg semaglutide), and two long-acting insulin analogs
2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes