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Seek medical advice before starting Wegovy if you have : Uncontrolled or recently diagnosed hypothyroidism Personal or family history of thyroid cancer (particularly medullary thyroid carcinoma) Multiple endocrine neoplasia syndrome type 2 Recent changes to levothyroxine dosing Symptoms suggesting inadequate thyroid hormone replacement Pregnancy, planning pregnancy, or breastfeeding Severe kidney problems Contact your healthcare provider during Wegovy treatment if you experience : Symptoms of thyroid dysfunction : fatigue, cold intolerance, weight changes beyond expected, hair loss, or palpitations Neck symptoms : persistent lump, swelling, pain, or difficulty swallowing Severe gastrointestinal side effects : persistent vomiting or diarrhoea that might affect medication absorption Signs of over- or under-replacement : anxiety, tremor, heat intolerance (over-replacement) or lethargy, constipation, depression (under-replacement) Seek urgent medical attention if you develop : Severe, persistent abdominal pain (possible pancreatitis) Signs of allergic reaction (rash, swelling, difficulty breathing) Regular follow-up appointments are essential for patients with hypothyroidism using Wegovy

Sudden weight loss can lower estrogen levels, delay ovulation, or cause temporary amenorrhea (missed periods)
*Correspondence: Xue Li, [email protected] This article was submitted to Inflammation, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Most research has focused on how well semaglutide controls blood sugar and helps with weight loss
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