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Interestingly, these molecules have several overlapping pharmacological effects, such as suppression of gastric emptying, reduction of glucagon secretion and weight loss in common

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| 1 Youre not in a calorie deficit | 2 Youre in a weight-loss plateau | 3 Your current dose isnt high enough to promote lower hunger | Practical strategies | Frequently asked questions | Take home message The main reasons youre not losing weight on semaglutide (Wegovy/Ozempic) might be that youre not eating in a calorie deficit, youve hit a weight-loss plateau, or the current dose that youre on isnt high enough to lower your hunger to the point where youre eating less

Porter JB, Hunter J, Jick H et al

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However, more advanced options like hormone replacement therapy or medications like Semaglutide and Tirzepatide can help you lose 10% to 20% of your initial body weight within a few months