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By blocking NNMT, it prevents the methylation and disposal of nicotinamide, raising intracellular NAD+ levels and activating SIRT1-mediated fat oxidation

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In our study, we utilized AA to induce colitis in a rat model, as it effectively increases intestinal mucosal vascular permeability and promotes inflammation and ulceration (46, 47)

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10.3389/fpubh.2017.00335 [DOI] [PMC free article] [PubMed] [Google Scholar] Khavinson VK, Izmaylov DM, Obukhova LK, Malinin VV (2000) Effect of epitalon on the lifespan increase in Drosophila melanogaster