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Levels under 1,200 mIU/mL usually double every 48 hours

This amide-type anesthetic inhibits nerve impulse conduction, offering effective localized anesthesia for various medical procedures

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More frequent, slower dose increases allow for improved outcomes with lower risk of side effects

Biorg Med Chem 25:61806189 Bekaii-Saab T, Wesolowski R, Ahn DH, Wu C, Mortazavi A, Lustberg M, Ramaswamy B, Fowler J, Wei L et al (2019) Phase I immunotherapy trial with two chimeric HER-2 B-cell peptide vaccines emulsified in montanide ISA 720VG and nor-MDP adjuvant in patients with advanced solid tumors phase I immunotherapy trial with two B-cell vaccines

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