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GLP-1 (Glucagon-Like Peptide-1), released after meals, enhances insulin release and signals fullness but may be impaired in those with diabetes or obesity

Dunlay SM, et al

In prostate cancer models, HTY has been reported to influence androgen receptorrelated signaling, which is relevant to hormone-driven tumor growth

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It is essential for maintaining healthy nerve cells, producing DNA, and aiding in the formation of red blood cells

However, the activation energy can be lowered (and the isomerization catalyzed) by changes that favor the single-bonded form, such as placing the peptide group in a hydrophobic environment or donating a hydrogen bond to the nitrogen atom of an X-Pro peptide group