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The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-alpha Expression in Macrophages

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A class of drugs that produces durable weight loss while also modulating systemic inflammation is exactly the class you would test in obesity-associated asthma

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11 Proglucagon (160aa residues) is then produced in these tissues by the removal of the signal peptide from the preproglucagon protein

Beyond weight loss, GLP-1 analogues have other health benefits