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At recommended doses, glutathione stores remain sufficient

Retrieved from American Academy of Dermatology

We hence explored the molecular changes induced by slowing down mitochondrial translation, and uncovered that a conserved program for mitochondrial-cytosolic translational balance is activated upon repression of mitochondrial translation 16

The safety profile of topical and oral glutathione seems to be reasonable

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Other potential challenges include anatomical barriers of the anterior eye that limit glutathione delivery to the lens and intracellular barriers within the lens that limit glutathione delivery to different lens regions