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Annatto has also been studied for its UV-protective, skin-reparative effects, making it a natural colorant with skin benefits 9

The compound inhibits the NNMT enzyme in fat cells, which increases cellular NAD+ levels and shifts adipocyte metabolism from fat storage to fat burning

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It plays roles in cell migration, inflammation regulation, wound healing, and angiogenesis

Biotin facilitates the metabolism of nutrients that feed beneficial gut bacteria, helping maintain a balanced microbiome that supports immune function

In the RHEA@Gel and G-RHEA@Gel groups, hardly any red fluorescence was detected