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CAFs significantly increase the catabolism of BCAAs and the secretion of BCKAs in the nutrient-poor tumor microenvironment (TME)

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But other times it seems to block the effects of glutamate

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Press release: Safety, pharmacokinetics, and pharmacodynamics of CT-996, an oral small-molecule, signal-biased GLP-1 receptor agonist over 4 weeks in adults with obesity