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They are expensive because pharmaceutical manufacturers have spent billions of dollars on R&D to get FDA approval

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Tokyo, Japan) were transformed with pGEX-4 T-1, pGEX-4 T-1-GIP, and pGEX-4 T-1-GLP-1 and cultured for 3 h in 200 mL Luria broth containing 0.1 mM isopropyl -D-thiogalactopyranoside (Wako Pure Chemicals, Osaka, Japan)

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It also contains a deletion of 70 amino acid residues from the C-terminus, a region that is highly flexible and that contains an immunodominant linear epitope that is strongly targeted by non-nAbs in convalescent COVID-19 plasma