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In this regard, Takahashi A

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First-generation GLP-1 receptor agonists necessitated once or twice-daily dosing, resulting in substantial peak-to-trough variations that caused inconsistent glycaemic regulation and heightened gastrointestinal adverse effects (Nauck and Meier 2019)

Cardiovasc Drugs Ther (2019) 33(6):6617

Consequently, several therapeutic approaches have aimed to antagonize GCG activity in the management of T2DM

Calculation basis: Each row uses the full 10 mg vial and a pump verified to release 0.10 mL per complete actuation