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Several agents, including glucagon-like peptide-1 and -aminobutyric acid, have been shown to promote cell proliferation, which is considered the main source of the regenerated cells in adult rodents, but with less clarity in humans

Subcutaneous injection delivers the peptide directly into systemic circulation, bypassing first-pass metabolism

Patients with heart failure with preserved ejection fraction and obesity who received tirzepatide had a lower risk of death from cardiovascular causes or worsening heart failure compared to placebo