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Compared to European populations, East Asian populations have a lower activation threshold of CITED4 under exercise load due to genetic factors, requiring only moderate-intensity exercise to induce cardiac chamber enlargement

And the North Carolina State Health Plan Board of Trustees voted last year to end coverage of GLP-1s for state employees, after then-North Carolina Treasurer Dale Folwells office estimated in 2023 that the drugs were projected to cost the State Health Plan $1 billion over the next six years

Notably, Ozempic and Wegovy were selected in January for a second round of Medicare drug price negotiations, which is expected to result in savings for the program and, possibly, for enrollees depending on their drug coverage