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This mechanism explains why patients report feeling full on 300-400 calories instead of their typical 1,200-calorie portions, without the hunger pangs of traditional dieting

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Notably, these benefits were achieved without undesirable estrogenic effects on the uterus

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5.4 Urosepsis and Pyelonephritis Serious urinary tract infections including urosepsis and pyelonephritis requiring hospitalization have been reported in patients receiving SGLT2 inhibitors, including dapagliflozin

10.1016/j.foodchem.2007.01.030 26 EyJ.SchmigE.TaubertD