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While the "right" time can vary slightly based on your specific goals, the general consensus among experts and seasoned users points to specific windows of opportunity that maximize the body's natural growth hormone (GH) production

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Reduction of TRT needs: Some men on testosterone replacement therapy (TRT) can reduce doses or discontinue entirely as natural production recovers with weight loss

A 3-4 day weekly program focused on compound lifts (squats, deadlifts, presses, rows) with progressive overload in the 6-12 rep range at 10-16 hard sets per muscle group weekly is optimal for muscle preservation during GLP-1 therapy

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