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Friedman notes that evidence from small randomized controlled trials and meta-analyses demonstrates meaningful reductions in Psoriasis Area and Severity Index (PASI) scores and corresponding improvements in quality-of-life measures with GLP-1 receptor agonists such as liraglutide and exenatide, including in patients without diabetes

As an animal study, the effects of the purified membrane protein may also not apply fully to human supplementation

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This is not a one size fits all scenario and reflecting No decision about me without me (Department of Health, 2012), the same considerations need to be applied in the PwDs decision to potentially not engage with this group GLP-1 RA start and opt for an individual one- to-one GLP-1 RA start instead

More information can be found under 'Periodic safety update reports: questions and answers'

In adults, registries have not shown major safety signals