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Funding This study was financed by the National Centre for Research and Development, Poland [Grant No.: LIDER/6/0016/L-11/19/NCBR/2020]

The M1 phenotype is often associated with disease, resulting in production and secretion of pro-inflammatory cytokines (i.e., tumor necrosis factor-alpha (TNF), interleukin-1 (IL-1), and IL-6), chemokines, and ROS to neutralize pathogens and increase cell recruitment to the site of inflammation

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They are fundamental biological processes that operate across all vascularized tissue types

Rodents treated with topical or systemic BPC-157 have been noted to experience reduced tissue inflammation, accelerated wound healing, and protection from damage caused by gonad-toxic agents

F., Gava, A