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Genetic variants influence receptor expression and signaling capacity, which may inform whether constipation is likely to be a prominent side effect or resolve quickly

and the cardiac muscle, which develops progressive cardiomyopathy

Your provider may recommend dietary changes, anti-nausea medication, or a temporary pause before resuming at a lower dose

The specific indications, preparations, and dosing regimens for each formulation must be carefully considered in clinical practice

If you plan to start retatrutide treatment for weight loss, consult your healthcare provider who will review your medical history, health goals, and decide if the medication is right for you.