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This work shows that the stabilized stem subunit could be a potential antigen for a SARS-CoV-2 universal vaccine against unpredictable variants. The study found immunization with the stem induced balanced Immunoglobulin G (IgG) antibodies with potent and broad ADCC activity, a type of immune reaction in which infected cells are coated with antibodies that then recruit certain types of white blood cells to kill the infected cells

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Look AHEAD Research Group, Gregg EW, Jakicic JM, et al

434 Many studies have shown that self-assembled peptide carriers modified with fusogenic peptides can overcome intracellular delivery obstacles

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Sustainable progress matters: The goal is not quick, temporary results