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GEP44 mediates insulin-independent glucose uptake in muscle via interactions with Y1-R GEP44 may also reduce serum glucose levels via direct interactions resulting in increased glucose uptake in muscle tissue

346,347,348 The first is the exogenous route, in which the NADs are directly introduced into the obtained exosomes via electroporation, co-incubation, sonication, extrusion, and freeze-thaw cycling

A drop of a 1% aqueous solution of phosphotungstic acid dye was used to stain the freshly made sample, which was then placed onto the surface of a carbon-coated copper grid for TEM visualization

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