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Participants aged 1875 years with biopsy-proven MASH and fibrosis stage F2-F3, with or without type 2 diabetes, and BMI 27.0 kg/m 2 , are randomised 1:2:2 to pemvidutide 1.2 mg or 1.8 mg once-weekly subcutaneously or placebo for 24 weeks (estimated enrolment: N = 190)