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224 In the pathogenesis of AD, the abnormal elevation of osteocyte-derived sclerostin may lead to cognitive impairment by inhibiting Wnt--catenin signaling in neurons through bone-brain crosstalk

10.1007/BF00390979 37 ButterfieldD

Many patients report improved sleep quality and reduced muscle tension when maintaining adequate magnesium levels during semaglutide therapy

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Ultimately, prospective studies evaluating bone outcomes with different GLP-1 RAs in this population, incorporating standardized DXA assessments and fracture surveillance, are needed to establish evidence-based skeletal health guidelines