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This is also the period when many women start GLP-1 medication, so you are adjusting to two new things simultaneously

This multi-target approach shows promise for managing both blood sugar levels and weight

This process must occur slowly and gently to prevent mechanical stress on the delicate peptide bonds

doi: 10.1001/jama.2023.19897 25

These include: Nausea Vomiting Diarrhoea Constipation Abdominal pain These side effects are typically mild to moderate, most common when starting the medication or increasing the dose, and often subside over time

Another GLP-1 analogue, lixisenatide, was reported to prevent the acuteness of cardiovascular events in apolipoprotein E / insulin receptor substrate 2 +/ (APOE / irs2 +/ ) mice by reducing the size of AS plaques, increasing plaque stability, and promoting the conversion of macrophages to the anti-inflammatory M2 phenotype (129)