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PMID: 37450427

A.et al (2019)

These ECM components undergo modifications by binding with soluble factors, including growth factors and other ECM-associated proteins (Ryan et al., 2007)

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 3% by weight of the poloxamer

What you need : Bacteriostatic water for reconstitution Insulin syringes (29-31 gauge) Alcohol swabs Standard protocol : Dose: 250-500mcg twice daily A 5mg vial lasts: 5-10 days (depending on dose) Total protocol: 4-8 weeks Cost per vial : $25-40 from reputable vendors

Users may inject what appears to be a full dose, but receive significantly less active medication