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3d and Supplementary Table 4), demonstrating improved in vivo peptide stability compared to unmodified GLP-1 analogue and exendin-4 fusions

In molecular docking models, it has been observed that curcumin fits into the active site of histone deacetylase HDAC8, forming contacts with residues Arg37, Pro35, Ile34, and Phe152 of the catalytic pocket

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