It is plausible that GSTs serve two distinct roles in the development of drug resistance via direct detoxification as well as acting as an inhibitor of the MAP kinase pathway
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Salehi B, Mishra AP, Nigam M, Sener B, Kilic M, Sharifi-Rad M, Fokou PVT, Martins N, Sharifi-Rad J (2018) Resveratrol: a double-edged sword in health benefits
The core features of hepatocyte apoptosis are associated with two main pathways: the extrinsic death receptor pathway and the intrinsic mitochondrial pathway [49]
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